Scientists from the John A. Moran Eye Center at the ÑÇÖÞ×ÔοÊÓƵ of Utah will share their latest research at the 2022 annual meeting in May.
ARVO is the largest community of eye and vision researchers in the world, with nearly 10,000 members from more than 75 countries.
Researchers from the Moran Eye Center’s 16 laboratories and centers are presenting on a wide range of work, from breakthroughs related to blinding diseases to new findings that deepen our understanding of vision itself.
View their presentation schedule below (times in U.S. MDT).
May 1
12:15 - 2:15 PM
Hierarchical Cluster Analysis of VEGF-induced STAT3-Mediated Genes in Human Retinal Microvascular Endothelial Cells
Author Block: Aniket Ramshekar, Colin Bretz, Mary Elizabeth Hartnett, MD
12:15 PM - 2:15 PM
Incidence of Retinal Detachment in Type 1 and Type 2 Stickler Syndrome
Author Block: Jessica Kraker, Mona Ame2, Lisa Schimmenti, Mary Elizabeth Hartnett, MD, Eileen Hwang, MD
1:57 - 2:14 PM
The Sensitivity and Specificity of FLIO (Fluorescence Lifetime Imaging Ophthalmoscopy) when Imaging Patients with MacTel
Author Block: Lydia Sauer, Alexandra Vitale, Paul Bernstein, MD
2:45 - 3:02 PM
CFAP418 functions in membrane lipid homeostasis through binding phosphatidic acid and cardiolipin during photoreceptor ciliogenesis
Author Block: Jun Yang, PhD, Anna Clark, Dongmei Yu, Daniel Zhu, Grace Neiswanger
2:45 – 4:45 PM
Lipid signaling and homeostasis in retinal health and disease
Moderators: Jason Miller, Julia Busik, Jun Yang, PhD, Goldis Malel
4:10 – 4:27 PM
Preclinical evaluation of RTC-1119, a surface eroding intracameral implant composed entirely of a latanoprost acid prodrug, for long-term intraocular pressure control
Author Block: Ike Ahmed, MD, Kyle Battiston, Shadi Taghavi, Hans Fischer, Emily Baldwin, Matthew Statham, Jonathan Day, Adam Daley, Ben Muirhead, Emily Anne Hicks, Jennifer Tian, Heather Sheardown, Ian Parrag, Wendy Naimark
5:15 – 5:32 PM
Individualized mesopic and dark-adapted fundus-controlled perimetry: Longitudinal changes in retinal sensitivity at the border of geographic atrophy.
Author Block: Monika Fleckenstein, MD, Leon von der Emde, Frank Holz, Steffen Schmitz-Valckenberg, MD, Maximilian Pfau
May 2
11:08 – 11:25 AM
Campana cells relay both rod- and cone-mediated visual signals to multiple RGC types
Author Block: Ning Tian, MD, PhD, Brent Young, Ping Wang
12:30 – 2:30 PM
AMD and Geographic Atrophy
Moderator: Steffen Schmitz-Valckenberg, MD
3:00 - 5:00 PM
Conditional Knockout of Scavenger Receptor B1 (SR-B1) from RPE Increases Free Cholesterol Accumulation in the RPE of the Bco2-/- Mice
Author Block: Binxing Li, PhD, Fu-Yen Chang1, Arunkumar Ranganathan1, Nathan Giauque1, Zihe Wan1, Paul Bernstein, MD
4:08 – 4:25 PM
Schlemm canal-targeted Tie2 knockdown (SC-Tie2 KD) as mouse model of adult-onset human glaucoma
Author Block: Alejandra Bosco, Cesar Romero, Joon Schwakopf, Oleg Yarishkin, J Cameron Millar, Michael Steele, David Krizaj, PhD, Monica Vetter
May 3
10:30 – 12:30 PM
Macular Carotenoids Lutein (L) and Zeaxanthin (Z) Protect Human Retinal Pigment Epithelial (RPE) Cells from Cobalt chloride-Induced Hypoxia Stress.
Author Block: Arunkumar Ranganathan, Binxing Li, PhD Paul Bernstein, MD
10:30 – 12:30 PM
Elovl4b Ablation in Zebrafish Leads to Loss of Ocular C30 to C34 Very-Long-Chain Polyunsaturated Fatty Acids
Author Block: Uzoamaka Nwagbo, Paul Bernstein, MD
11:21 – 11:38 AM
Quantification of lesion progression of incomplete and complete retinal pigment epithelium and outer retinal atrophy in age-related macular degeneration
Author Block: Steffen Schmitz-Valckenberg, MD, Marlene Sassmannshausen, Martina Braun, Verena Steffen, Simon Gao, Lee Honigberg, Daniela Ferrara, Maximilian Pfau, Frank Holz
12:30 - 2:30 PM
Comparison of segmentation methods for measuring collagen fiber density in confocal reflectance images of the vitreous
Author Block: Eileen Hwang, MD, Denise Morgan, Mary Elizabeth Hartnett, MD, Brittany Coats
12:30 - 2:30 PM
Maternal Uteroplacental Insufficiency Protects Offspring from Oxygen-Induced Vascular Loss Through Erythropoietin Receptor Mediated Signaling
Author Block: Thaonhi Cung, Eric Kunz, Haibo Wang, Aniket Ramshekar, Colin Bretz, Ashley Brown, Vladimir Divoky, Camille Fung, Mary Elizabeth Hartnett, MD
1:51 – 2:08 PM
Upregulation of Rod Ribbon Synapse Components Coincides with Well-preserved Scotopic Vision in the P23H Model of Retinitis Pigmentosa
Author Block: Frans Vinberg, PhD, Fatima Abbas, Elliot Choi, Marcin Tabaka, Umair Seemab, Krzysztof Palczewski. Henri Leinonen
3:30 – 5:30 PM
The Lutein and Zeaxanthin in Pregnancy (L-ZIP) Trial – Initial Results
Author Block: Emmanuel Kofi Addo, Aruna Gorusupudi, Susan Allman, Paul Bernstein, MD
3:30 – 5:30 PM
Retinopathy of Prematurity
Moderator: Mary Elizabeth Hartnett, MD, FACS, FARVO
3:30 – 5:30 PM
TRPV4 involvement in inflammation and tissue damage in corneal epithelium
Author Block: Luka Lapajne, Monika Lakk, Marko Hawlina, David Krizaj, PhD
3:00 PM - 5:00 PM
Prevalence of retinopathy of prematurity in Colombia
Author Block: Maria Parra, Francisco Arango, Silvia Granados, Harold Rodriguez, Mary Elizabeth Hartnett, MD
4:47 – 5:05 PM
Pathoconnectomics in Retinal Degeneration
Author Block: Bryan Jones, PhD
5:12 – 5:29 PM
Placental Inflammation Significantly Correlates with Reduced Risk for Retinopathy of Prematurity
Author Block: Leah Owen, MD, Charles Zhang, Blair Wood, Lara Carroll, Jessica Comstock, Margaret DeAngelis
May 4
10:00 – 12:00 PM
Electroretinography and disease
Authors: Matthew Van Hook and Frans Vinberg, PhD
12:30 - 2:30 PM
Subretinal fibrosis – clinical challenges, mechanism, and diagnostic tools
Moderator: Mary Elizabeth Hartnett, MD, FACS, FARVO and Heping Xu
12:30 - 2:30 PM
Comparison of segmentation methods for measuring collagen fiber density in confocal reflectance images of the vitreous
Author Block: Eileen Hwang, MD, Denise Morgan, Mary Elizabeth Hartnett, MD, FACS, FARVO, Brittany Coats
12:30 – 2:30 PM
Proteomic changes in the lens of a congenital cataract mouse model lead to reduced levels of glutathione and taurine
Author Block: Sheldon Rowan, Eloy Bejarano, Elizabeth Whitcomb, Rebecca Pfeiffer, Kristie Rose, Kevin Schey, Bryan Jones, PhD, Allen Taylor
12:30 -2:30 PM
Dynein Dysregulation Due to the Absence of NUDC leads to Mitochondrial Mislocalization and Dysfunction in Rod Photoreceptors
Author Block: Hailey Levi, Meredith Hubbard, Mary Anne Garner, TJ Hollingsworth, Ke Jiang, Nat Nelson, Anushree Gade, Drue Benefield, Guoxin Ying, PhD, Wolfgang Baehr, PhD, Bryan Jones, PhD, Anand Swaroop, Glenn Rowe, Alecia Gross
12:30 – 2:30 PM
Effects of Carotenoid Supplementation on the Lipid Profile of the Serum of a Transgenic Mouse
Author Block: Fu-Yen Chang, Arunkumar Ranganathan, Binxing Li, PhD, Paul Bernstein, MD
12:30 - 2:30 PM
Separately Imaging Zeaxanthin and Meso-zeaxanthin in the Human Fovea with Polarized Resonance Raman Microscopy
Author Block: Nathan Giauque1, Fu-Yen Chang1, Zihe Wan1, Binxing Li, PhD, Paul Bernstein, MD
3:00 - 5:00 PM
Phenotypic Differences of Punctate Inner Choroidopathy (PIC) and Multifocal Choroiditis (MFC) Utilizing Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO)
Author Block: Alexandra Vitale, Sean Collon, Lydia Sauer, Paul Bernstein, MD
May 12
8:00 – 9:30 AM
Anti-VEGF injections in the management of Retinopathy of Prematurity: What we learned in the last decade?
Special Interest Group: Mary Elizabeth Hartnett, MD FACS, Shunji Kusaka, Wei-Chi Wu, Swanti Agaral-Sinha